Gynecomastia - Pathology

 GYNECOMASTIA

Gynecomastia is a unilateral or bilateral benign breast enlargement in a male. It is usually caused by an altered androgen-estrogen balance that favors estrogen effect. Microscopically, it is characterized by:

 

•         Ductal epithelial hyperplasia

 

•         Ductal elongation and branching

 

•         Proliferation of periductal fibroblasts

 

•         Increase in vascularity in the involved tissue